숙신산

숙신산 속성

숙신산 MSDS

1,2-Ethanedicarboxylic acid

숙신산 C화학적 특성, 용도, 생산

물성

석신산은 흰색의 강한 신맛이 나는 냄새가 없는 고체이다.수용액에서 석신산은 쉽게 이온화되어 짝염기인 석시네이트를 형성한다.

화학 반응

석신산은 푸마르산으로 산화되거나 다이에틸석시네이트(diethylsuccinate, (CH2CO2CH2CH3)2)와 같은 다이에스터로 전환될 수 있다. 이러한 다이에틸 에스터(diethyl ester)는 스토브 축합(Stobbe condensation) 반응의 기질이다. 석신산의 탈수는 석신산 무수물을 생성한다. 석신산은 1,4-뷰테인다이올, 말레산 무수물, 석신이미드, 2-피롤리디논 및 테트라하이드로푸란을 유도하는데 사용될 수 있다.

용도

석신산은 일부 폴리에스터의 전구물질이며, 일부 알키드 수지의 구성 성분이다.석신산은 또한 조직공학 분야와 관련이 있는 특정 생분해성 고분자의 기초 역할을 한다.식품 첨가물 및 식이 보충제로서 석신산은 미국 식품의약국에서 GRAS(Generally Recognized As Safe, 식품 첨가물에 대한 미국 식품의약국(FDA)의 합격증)로 인정되었다.

순도시험

  (1) 융점 : 이 품목의 융점은 185～190℃이어야 한다.

  (2) 납 : 이 품목 5.0g을 취하여 원자흡광광도법 또는 유도결합플라즈마발광광도법에 따라 시험할 때, 그 양은 5.0ppm 이하이어야 한다.

  (3) 수은 : 이 품목을 수은시험법에 따라 시험할 때, 그 양은 1.0ppm 이하이어야 한다.

  (4) 산화되기 쉬운 물질 : 이 품목 1g에 물 25mL 및 묽은황산 25mL를 가하여 녹이고 이를 20℃로 유지하면서 0.1N 과망간산칼륨용액 4mL를 가할 때, 시액의 색은 3분 이내에 없어져서는 아니 된다.

  (5) 비소 : 이 품목을 비소시험법에 따라 시험할 때, 그 양은 4.0ppm 이하이어야 한다.

확인시험

  이 품목은 확인시험법 중 호박산염의 반응을 나타낸다.

정량법

  이 품목 약 1g을 정밀히 달아 물에 녹여 250mL로 하고 그 중 25mL를 취하여 0.1N 수산화나트륨용액으로 적정한다(지시약 : 페놀프탈레인시액 2～3방울).

0.1N 수산화나트륨용액 1mL ＝ 5.904mg C₄H₆O₄

강열잔류물

  이 품목의 강열잔류물은 0.025% 이하이어야 한다.

화학적 성질

Succinic acid,C02H(CH2)2C02H, also known as butanedioic acid,butane diacid, and amber acid, is a colorless odorless prisms or white crystalline powder that melts at 185°C (364 of). Soluble in water and alcohol, it is used as a chemical intermediate, Succinic acid is used in lacquers,medicine,dyes,and as a taste modifier.

용도

succinic acid is widely use as organic intermediates for the pharmaceutical, engineering plastics, resins etc.. For the synthesis of sedatives, contraceptives and cancer drugs in the pharmaceutical industry. In the chemical industry for the production of dyes, alkyd resin, glass fiber reinforced plastics, ion exchange resins and pesticides.

정의

ChEBI: An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.

일반 설명

White crystals or shiny white odorless crystalline powder. pH of 0.1 molar solution: 2.7. Very acid taste.

공기와 물의 반응

Slightly water soluble.

반응 프로필

Succinic acid reacts exothermically to neutralize bases, both organic and inorganic. Can react with active metals to form gaseous hydrogen and a metal salt. Such reactions are slow in the dry, but systems may absorb water from the air to allow corrosion of iron, steel, and aluminum parts and containers. Reacts slowly with cyanide salts to generate gaseous hydrogen cyanide. Reacts with solutions of cyanides to cause the release of gaseous hydrogen cyanide. May generate flammable and/or toxic gases and heat with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. May react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Can be oxidized exothermically by strong oxidizing agents and reduced by strong reducing agents. May initiate polymerization reactions.

화재위험

Flash point data for Succinic acid are not available. Succinic acid is probably combustible.

Safety Profile

Moderately toxic by subcutaneous route. A severe eye irritant. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Carcinogenicity

Monosodium succinate was given to groups of 50 male and 50 female Fischer 344 rats in drinking water at levels of 0%, 1%, or 2% for 2 years. No toxic lesion specifically caused by long-term administration of monosodium succinate was detected, and no dose-related increase was found in the incidence of tumors in any organ or tissue. The incidence of C-cell tumors of the thyroid gland of females that received 2% solution was apparently, but not significantly, higher than that in controls. Because C-cell tumors are commonly occurring spontaneous tumors in aging female rats of this strain and the incidence of C-cell tumors in the female control group was lower than that of historical controls for the testing laboratory, the authors concluded that this lesion was not treatment related.

Purification Methods

Wash it with diethyl ether. Crystallise it from acetone, distilled water, or tert-butanol. Dry it under vacuum over P2O5 or conc H2SO4. Also purify it by conversion to the disodium salt which, after crystallisation from boiling water (charcoal), is treated with mineral acid to regenerate the succinic acid. The acid is then recrystallised and dried in a vacuum. [Beilstein 2 H 606, 2 IV 1908.]

숙신산 준비 용품 및 원자재

원자재

준비 용품

숙신산 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55
Shandong Zhishang New Material Co., Ltd.	+8617653113209	sales002@sdzschem.com	China	3050	58
Henan Xiangduo Industry Co., Ltd.	+86-15981848961 +86-15981848961	sales@xiangduochem.com	China	497	58
Handan Huajun chemicals Co.,Ltd	+86-0310-8166573 +8618630058311	sales@huajunchem.com	China	28	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2968	58
Nanjing Deda New Material Technology Co., Ltd	+8613223293093	bella@njdeda.com	China	81	58
Hebei Dangtong Import and export Co LTD	+8615632927689	admin@hbdangtong.com	China	990	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	1000	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	16803	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	sarah@tnjone.com	China	964	58

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