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ChemicalBook > Produktkatalog >Bio- und Chemieingenieurwesen >Gängige Aminosäuren und Eiweißpräparate >L-Lysin

L-Lysin Produkt Beschreibung

CAS-Nr.56-87-1
Bezeichnung:L-Lysin
Englisch Name:L-Lysine
Synonyma:
Lys;LYSINE;L-Lys-OH;L-LYSINE;H-LYS-OH;FEMA 3847;Aminutrin;lysineacid;L-LysineUSP;Lysine acid
CBNumber:CB4492106
Summenformel:C6H14N2O2
Molgewicht:146.19
MOL-Datei:56-87-1.mol
L-Lysin physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 215 °C (dec.)(lit.)
alpha : D20 +14.6° (c = 6.5); D23 +25.9° (c = 2 in 6.0N HCl)
Siedepunkt:: 265.81°C (rough estimate)
Dichte: 1.1360 (rough estimate)
Brechungsindex: 26 ° (C=2, 5mol/L HCl)
FEMA : 3847 | L-LYSINE
storage temp. : Store at RT.
Löslichkeit: H2O: 0.1 g/mL, clear, colorless
pka: 2.16(at 25℃)
Aggregatzustand: Powder or Crystals
Farbe: White to light yellow
Optische Aktivität: [α]20/D +26.0±1.0°, c = 2% in 6 M HCl
Wasserlöslichkeit: Soluble in water. Insoluble in ethanol, ethyl ether, acetone, benzene and common neutral solvent.
Merck : 14,5636
JECFA Number: 1439
BRN : 1722531
Stabilität:: Stable. Incompatible with strong oxidizing agents.
InChIKey: KDXKERNSBIXSRK-YFKPBYRVSA-N
CAS Datenbank: 56-87-1(CAS DataBase Reference)
NIST chemische Informationen: Lysine(56-87-1)
EPA chemische Informationen: L-Lysine(56-87-1)
Sicherheit
Kennzeichnung gefährlicher: Xi
S-Sätze:: 24/25
WGK Germany : 3
RTECS-Nr.: OL5540000
TSCA : Yes
HS Code : 29224110
Giftige Stoffe Daten: 56-87-1(Hazardous Substances Data)

L-Lysin Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
See ι-LYSINE MONOCHLORIDE.
Chemische Eigenschaften
L-Lysine is an essential amino acid (a protein building block) that cannot be produced by the body from other nutri ents. It helps ensure adequate absorption of calcium and the formation of collagen for bone, cartilage and connective tissue. This compound is odorless.
Chemische Eigenschaften
White to pale yellow crystalline powder
Occurrence
Some natural food sources for l-lysine include lima beans, kidney beans, potatoes, corn, red meat, fish and milk.
Verwenden
Essential amino acid for human development. Lysine residues are useful in many cellular processes, due to their ability to accept a wide variety of post-translational modifications.
Verwenden
A moderate serotonin antagonist and essential amino acid.
Verwenden
lysine is a skin-conditioning amino acid.
Definition
ChEBI: An L-alpha-amino acid; the L-isomer of lysine.
synthetische
Produced by fermentation. Also produced by use of continuous ion exchange technology.
Biotechnologische Produktion
C. glutamicum and, to a lesser extent, E. coli are the main organisms used today for industrial L-lysine production. The first L-producing strains based on C. glutamicum were reported in 1961, and those based on E. coli in 1995. The advantages of using E. coli versus C. glutamicum include the achievement of higher growth rates at higher fermentation temperatures. The formation of lysine is highly influenced by two enzymes, aspartate kinase (AK) and homoserine dehydrogenase (HDH). AK converts aspartate into aspartate semialdehyde, and is highly feedback-inhibited by lysine and threonine. HDH converts aspartate semialdehyde into homoserine, which is an intermediate for the biosynthesis of threonine, methionine, and isoleucine. L-Lysine–producing strains therefore often contain a deregulated AK and/or a reduced activity HDH. Despite the improvement of the flux from aspartate towards lysine, the availability of key metabolites from the central metabolic pathways is also essential. Here the formation of oxaloacetate directly from phosphoenol pyruvate or via pyruvate is essential for the carbon yield as some unnecessary cycles are included. For example, inactivation of the enzyme phosphoenol pyruvate carboxykinase, which catalyzes the reverse reaction from oxaloacetate to phosphoenol pyruvate gave an improvement in lysine formation. By overexpression of pyruvate carboxylase, the conversion yield of glucose to lysine could be increased by 50 %. With a synthetic lysine hyperproducing strain, containing 12 defined modifications from the wild type, a carbon yield of 0.55 g/g and a product titer of 120 g/L over 30 h fermentation could be obtained.
Today, however, the main commercial process for L-lysine remains the fermentation of C. glutamicum. This is performed in fed-batch mode in large-scale fermenters of up to 500 m3 volume, with production capacities in excess of 100,000 tonnes. The commercial manufacturing process has been comprehensively described by Pfefferle.
Aroma threshold values
Detection: 500 ppm
Sicherheitsprofil
An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
läuterung methode
Crystallise L-lysine from aqueous EtOH. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2097-2122 1961, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]
L-Lysin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
2,4,6-Trinitrophenol Pimelinsure Harnstoff Hydrogenchlorid Natriumhydroxid Strke Caseine epsilon-Caprolactam Holzkohle, aktiviert Calciumdihydroxid Ammoniak, wasserfrei
Downstream Produkte
L-Aspartsure, Verbindung mit L-Lysin (1:1) Lysinhydrochlorid Lisinopril L-Lysinhydrochlorid Pentamethylendiamin
L-Lysin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 380)Lieferanten     
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95sales@capotchem.com China 19919 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21924 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788Candy@bj-chem.com CHINA 495 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733sales@mainchem.com CHINA 32457 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012sales03@shyrchem.com CHINA 661 60
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684info@tnjchem.com China 1750 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20516 58
 
56-87-1(L-Lysin)Verwandte Suche:
L-Threonin L-Isoleucin 3-Phenyl-L-alanin Hexansure DL-Lysin Lypressin L-Lysinmono[4-isobutyl-α-methylbenzolacetat] N6-(tert-Butoxycarbonyl)-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysin N2-(tert-Butoxycarbonyl)-N6-formyl-L-lysin L-Lysindihydrochlorid L-Lysin L-Lysinmonoacetat POLYLYSINE
L - LYSINE FREE BASE (ANHYDROUS) L-Lizine cormob crystalline L-LYSINE (BASE) pure L-LYSINE BASE MONOHYDRATE pure L-Lysine,98+% L-LYSINE CRYST.RESEARCH GRADE L-Lysine,(S)-2,6-Diaminocaproic acid LYSINE, L-(+)-(P) (S)-2,6-diaMinohexanoic acid hydrate (S)-a,e-Diaminocaproic acid Aminutrin, 6-amino- L-Lysine (9CI) (2S)-2,6-Diaminocaproic acid, (2S)-2,6-Diaminohexanoic acid L-Lysine crystallized, >=98.0% (NT) L-Lysine Vetec(TM) reagent grade, >=98% NEODIMIUM STAND L-Lys-OH L-Lysine≥ 99% (Titration) (S)-2,6-DIAMINOCAPROIC ACID (S)-(+)-LYSINE LYSINE LYSINE, L-(+)- L-(+)-LYSINE L-Norleucine, 6-amino- Lysine, L- (8CI) L-LysineUSP (S)-2,6-Diaminohexanoic acid L-(+)-LYSINE 50% SOLUTION L-LYSINE L-LYSINE BASE H-LYS-OH FEMA 3847 2,6-DIAMINOCAPROIC ACID (S)-alpha,epsilon-Diaminocaproic acid 2,6-Diaminohexanoic acid 2,6-diaminohexanoicacid alpha,epsilon-Diaminocaproic acid alpha,epsilon-diaminocaproicacid alpha-Lysine Aminutrin Hexanoic acid, 2,6-diamino-, (S)- L-,-Diaminocar-proicacid L-H2N(CH2)4CH(NH2)COOH L-Lysine, l.s. Lys lys(iupacabbreviation) Lysine acid lysineacid L-Lysine Free Base L-LYSINE NON-ANIMAL SOURCE, CELL CULTURE TESTED L-LYSINE, 97% (98% EE/GLC) L(+)-LYSINE-1-HYDRATE BIOSYNTH L-LYSINE SOLUTION, 50% IN WATER L-LYSIN, KRISTALLISIERT L-LYSINE MONOHYDRATE 98% L-Lysine~97% L-Lysine50%SolutionInWater L-Lysine (non-medicinal)
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