ChemicalBook
Chinese English Japanese Germany Korea

L-리신

L-리신
L-리신 구조식 이미지
카스 번호:
56-87-1
한글명:
L-리신
동의어(한글):
리신;L-라이신;L-리신
상품명:
L-Lysine
동의어(영문):
Lys;LYSINE;L-Lys-OH;L-LYSINE;H-LYS-OH;FEMA 3847;Aminutrin;lysineacid;L-LysineUSP;Lysine acid
CBNumber:
CB4492106
분자식:
C6H14N2O2
포뮬러 무게:
146.19
MOL 파일:
56-87-1.mol

L-리신 속성

녹는점
215 °C (dec.)(lit.)
알파
D20 +14.6° (c = 6.5); D23 +25.9° (c = 2 in 6.0N HCl)
끓는 점
265.81°C (rough estimate)
밀도
1.1360 (rough estimate)
굴절률
26 ° (C=2, 5mol/L HCl)
FEMA
3847 | L-LYSINE
저장 조건
Store at RT.
용해도
H2O: 0.1 g/mL, clear, colorless
산도 계수 (pKa)
2.16(at 25℃)
물리적 상태
Powder or Crystals
색상
White to light yellow
optical activity
[α]20/D +26.0±1.0°, c = 2% in 6 M HCl
수용성
Soluble in water. Insoluble in ethanol, ethyl ether, acetone, benzene and common neutral solvent.
Merck
14,5636
JECFA Number
1439
BRN
1722531
안정성
Stable. Incompatible with strong oxidizing agents.
InChIKey
KDXKERNSBIXSRK-YFKPBYRVSA-N
CAS 데이터베이스
56-87-1(CAS DataBase Reference)
NIST
Lysine(56-87-1)
EPA
L-Lysine(56-87-1)

안전

위험품 표기 Xi
안전지침서 24/25
WGK 독일 3
RTECS 번호 OL5540000
TSCA Yes
HS 번호 29224110
유해 물질 데이터 56-87-1(Hazardous Substances Data)

L-리신 MSDS


L-Lysine

L-리신 C화학적 특성, 용도, 생산

개요

See ι-LYSINE MONOCHLORIDE.

화학적 성질

L-Lysine is an essential amino acid (a protein building block) that cannot be produced by the body from other nutri ents. It helps ensure adequate absorption of calcium and the formation of collagen for bone, cartilage and connective tissue. This compound is odorless.

화학적 성질

White to pale yellow crystalline powder

출처

Some natural food sources for l-lysine include lima beans, kidney beans, potatoes, corn, red meat, fish and milk.

용도

Essential amino acid for human development. Lysine residues are useful in many cellular processes, due to their ability to accept a wide variety of post-translational modifications.

용도

A moderate serotonin antagonist and essential amino acid.

용도

lysine is a skin-conditioning amino acid.

정의

ChEBI: An L-alpha-amino acid; the L-isomer of lysine.

제조 방법

Produced by fermentation. Also produced by use of continuous ion exchange technology.

생명 공학 생산

C. glutamicum and, to a lesser extent, E. coli are the main organisms used today for industrial L-lysine production. The first L-producing strains based on C. glutamicum were reported in 1961, and those based on E. coli in 1995. The advantages of using E. coli versus C. glutamicum include the achievement of higher growth rates at higher fermentation temperatures. The formation of lysine is highly influenced by two enzymes, aspartate kinase (AK) and homoserine dehydrogenase (HDH). AK converts aspartate into aspartate semialdehyde, and is highly feedback-inhibited by lysine and threonine. HDH converts aspartate semialdehyde into homoserine, which is an intermediate for the biosynthesis of threonine, methionine, and isoleucine. L-Lysine–producing strains therefore often contain a deregulated AK and/or a reduced activity HDH. Despite the improvement of the flux from aspartate towards lysine, the availability of key metabolites from the central metabolic pathways is also essential. Here the formation of oxaloacetate directly from phosphoenol pyruvate or via pyruvate is essential for the carbon yield as some unnecessary cycles are included. For example, inactivation of the enzyme phosphoenol pyruvate carboxykinase, which catalyzes the reverse reaction from oxaloacetate to phosphoenol pyruvate gave an improvement in lysine formation. By overexpression of pyruvate carboxylase, the conversion yield of glucose to lysine could be increased by 50 %. With a synthetic lysine hyperproducing strain, containing 12 defined modifications from the wild type, a carbon yield of 0.55 g/g and a product titer of 120 g/L over 30 h fermentation could be obtained.
Today, however, the main commercial process for L-lysine remains the fermentation of C. glutamicum. This is performed in fed-batch mode in large-scale fermenters of up to 500 m3 volume, with production capacities in excess of 100,000 tonnes. The commercial manufacturing process has been comprehensively described by Pfefferle.

Aroma threshold values

Detection: 500 ppm

Safety Profile

An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise L-lysine from aqueous EtOH. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2097-2122 1961, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]

L-리신 준비 용품 및 원자재

원자재

준비 용품


L-리신 공급 업체

글로벌( 380)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19919 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21924 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 495 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 661 60
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1750 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20516 58

Copyright 2019 © ChemicalBook. All rights reserved