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히드로염화 아밀로리드

히드로염화 아밀로리드
히드로염화 아밀로리드 구조식 이미지
카스 번호:
2016-88-8
한글명:
히드로염화 아밀로리드
동의어(한글):
히드로염화아밀로리드;히드로염화아밀로리드(AMILORIDEHYDROCHLORIDE)
상품명:
Amiloride hydrochloride
동의어(영문):
Arumil;AMipraMizi;AMIPRAMIDIN;amiprazidine;AMIPRAMIZIDE;AMipraMidine;GUANAMPRAZINE;AMILORIDE HCL;amiloridechloride;HCL AMILORIDE HCL
CBNumber:
CB5290772
분자식:
C6H8ClN7O.ClH
포뮬러 무게:
266.09
MOL 파일:
2016-88-8.mol

히드로염화 아밀로리드 속성

녹는점
293-294°C
저장 조건
Store at RT
용해도
H2O: 50 mg/mL, clear, yellow-green
물리적 상태
powder
색상
yellow
수용성
<0.1 g/100 mL at 19.5 ºC
CAS 데이터베이스
2016-88-8(CAS DataBase Reference)
EPA
Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)- 6-chloro-, monohydrochloride(2016-88-8)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T,Xi
위험 카페고리 넘버 25-36/37/38
안전지침서 36-45-26
유엔번호(UN No.) UN 2811 6.1/PG 3
WGK 독일 3
RTECS 번호 UQ2275500
위험 등급 6.1(a)
포장분류 II
HS 번호 29339980
그림문자(GHS):
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H301 삼키면 유독함 급성 독성 물질 - 경구 구분 3 위험 P264, P270, P301+P310, P321, P330,P405, P501
예방조치문구:

히드로염화 아밀로리드 MSDS


Amiloride hydrochloride

히드로염화 아밀로리드 C화학적 특성, 용도, 생산

화학적 성질

Pale Yellow Solid

용도

Na+ channel inhibitor, diuretic

용도

A calcium channel andsodium channel protein inhibitor

용도

Sodium channel blocker. Diuretic.

정의

ChEBI: A hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid.

상표명

Midamor (Merck).

일반 설명

Crystalline solid or very light yellow powder.

공기와 물의 반응

Insoluble in water.

반응 프로필

A halogenated amine and amide, acidic salt. In aqueous solution, behaves as a weak acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

건강위험

SYMPTOMS: Symptoms of exposure to Amiloride hydrochloride include headache, weakness, fatigue, back, chest, neck, shoulder or extremity pain; nausea, anorexia, vomiting, abdominal pain, hyperkalemia, paresthesias, shock, dizziness, coughing, shortness of breath, depression, nervousness, flaccid paralysis of the extremities, bradycardia, flatulence, skin rash, gas pain, constipation and dyspnea.

화재위험

Flash point data for Amiloride hydrochloride are not available; however, Amiloride hydrochloride is probably combustible.

생물학적 활성

Na + channel blocker. Defines the I 2A -amiloride sensitive and I 2B -amiloride insensitive imidazoline binding sites. Also inhibits TRPP3 channels.

히드로염화 아밀로리드 준비 용품 및 원자재

원자재

준비 용품


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