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Darifenacin hydrobromide

Darifenacin hydrobromide
Darifenacin hydrobromide structure
CAS No.
133099-07-7
Chemical Name:
Darifenacin hydrobromide
Synonyms
Emsele;Enablex;Emselex;UK 88525-04;Darifenacin HCl;DARIFENACIN HBR;Darifenacin hydrobro;DARFENACIN HYDROBROMIDE;Darifenacin Hydrobromid;darifenacin hydrobromide
CBNumber:
CB9855171
Molecular Formula:
C28H29BrN2O2
Formula Weight:
505.44606
MOL File:
133099-07-7.mol

Darifenacin hydrobromide Properties

Melting point:
228-2300C
alpha 
25D -30.3° (c = 1.0 in methylene chloride)
storage temp. 
-20°C Freezer
solubility 
DMSO: soluble20mg/mL, clear
form 
powder
color 
white to beige
optical activity
[α]/D +41 to +49°, c = 1 in methylene chloride
CAS DataBase Reference
133099-07-7(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
HS Code  2934990002

Darifenacin hydrobromide price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1102 Darifenacin hydrobromide ≥98% (HPLC) 133099-07-7 10mg $55.1 2018-11-13 Buy
Sigma-Aldrich SML1102 Darifenacin hydrobromide ≥98% (HPLC) 133099-07-7 50mg $235 2018-11-13 Buy
Cayman Chemical 14424 Darifenacin (hydrobromide) ≥95% 133099-07-7 10mg $65 2018-11-13 Buy
Cayman Chemical 14424 Darifenacin (hydrobromide) ≥95% 133099-07-7 25mg $154 2018-11-13 Buy
Cayman Chemical 14424 Darifenacin (hydrobromide) ≥95% 133099-07-7 50mg $293 2018-11-13 Buy

Darifenacin hydrobromide Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Darifenacin hydrobromide is used as a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor.

Uses

calcium replenisher

Uses

acute lymphoblastic leukemia therapeutic

Definition

ChEBI: The hydrobromide salt of darifenacin. A selective antagonist for the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions, it is used in the management of urinary incontinence.

brand name

Enablex (Novartis).

General Description

Darfenacin (Enablex),(s)-2-{1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidinyl}-2,2-diphen-ylacetamide, is an antimuscarinicagent that has selectivity for the M3 muscarinicsubtype receptor. By competitively blocking of the muscarinicreceptors results in a reduction of the smoothmuscle tone, allowing for greater volume of urine to bestored in the bladder. This results in less urinary incontinence,urgency, and frequency. It is a white to almostwhite, crystalline powder, with a molecular weight of507.5. Darifenacin is metabolized by the isozymesCYP2D6 and CYP3A4 with the primary metabolic routesbeing monohydroxylation of the dihydrobenzofuran ring,opening of the dihydrobenzofuran ring, and N-dealkylationof the pyrrolidine nitrogen.

Darifenacin hydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products


Darifenacin hydrobromide Suppliers

Global( 166)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21671 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1817 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2908 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Jinan Shengqi pharmaceutical Co,Ltd
86+18663751872
christine@shengqipharm.com CHINA 556 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58

View Lastest Price from Darifenacin hydrobromide manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Darifenacin hydrobromide
133099-07-7
US $1.00 / KG 1G 98% 100KG career henan chemical co

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