1,4-부탄디올
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1,4-부탄디올 속성
- 녹는점
- 16 °C (lit.)
- 끓는 점
- 230 °C (lit.)
- 밀도
- 1.017 g/mL at 25 °C (lit.)
- 증기 밀도
- 3.1 (vs air)
- 증기압
- <0.1 hPa (20 °C)
- 굴절률
- n
20/D 1.445(lit.)
- 인화점
- 135 °C
- 저장 조건
- Store below +30°C.
- 산도 계수 (pKa)
- 14.73±0.10(Predicted)
- 물리적 상태
- 액체
- 색상
- 무색의
- 냄새
- 냄새 없는
- 수소이온지수(pH)
- 7-8 (500g/l, H2O, 20℃)
- 폭발한계
- 1.95-18.3%(V)
- 수용성
- 혼용 가능
- 감도
- Hygroscopic
- BRN
- 1633445
- Dielectric constant
- 30.0(30℃)
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제, 무기산, 산 염화물, 산 무수물과 호환되지 않습니다.
- InChIKey
- WERYXYBDKMZEQL-UHFFFAOYSA-N
- LogP
- -0.88 at 25℃
- CAS 데이터베이스
- 110-63-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 22-67 | ||
안전지침서 | 36-23-24/25 | ||
WGK 독일 | 1 | ||
RTECS 번호 | EK0525000 | ||
자연 발화 온도 | 698 °F | ||
TSCA | Yes | ||
HS 번호 | 29053980 | ||
유해 물질 데이터 | 110-63-4(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: 1525 mg/kg LD50 dermal Rabbit > 2000 mg/kg | ||
기존화학 물질 | KE-03788 |
1,4-부탄디올 C화학적 특성, 용도, 생산
화학적 성질
1,4-butanediol (1,4-BD) is a colorless, viscous liquid derived from butane by placement of alcohol groups at each end of its molecular chain and is one of four stable isomers of butanediol.the hydroxyl function of each end group of the Butanediol reacts with different mono- and bifunctional reagents: for example with dicarboxylic acids to polyesters, with diisocyanates to polyurethanes, or with phosgene to polycarbonates. 1.4-Butanediol (BDO) is a high-quality intermediate. BDO and its derivatives are widely used for producing plastics, solvents, electronic chemicals and elastic fibers. Additionally BDO is also a building block for the synthesis of polyesterpolyols and polyetherpolyols. BASF is the most significant producer of 1,4-Butanediol and its derivatives worldwide.용도
- Butanediol and its derivatives is used in a broad spectrum of applications in the chemical industry; amongst others in the manufacturing of technical plastics, polyurethanes, solvents, electronic chemicals and elastic fibres.
- 1,4-Butanediol is used in the synthesis of epothilones, a new class of cancer drugs. Also used in the stereoselective synthesis of (-)-Brevisamide.
- 1,4-Butanediol's largest use is within tetrahydrofuran (THF) production, used to make polytetramethylene ether glycol, which goes mainly into spandex fibers, urethane elastomers, and copolyester ethers.
- It is commonly used as a solvent in the chemical industry to manufacture gamma-butyrolactone and elastic fibers like spandex.
- It is used as a cross-linking agent for thermoplastic urethanes, polyester plasticizers, paints and coatings.
- It undergoes dehydration in the presence of phosphoric acid yielded teterahydrofuran, which is an important solvent used for various applications.
- It acts an intermediate and is used to manufacture polytetramethylene ether glycol (PTMEG), polybutylene terephthalate (PBT) and polyurethane (PU).
- It finds application as an industrial cleaner and a glue remover.
- 1,4-butanediol is also used as a plasticiser (e.g. in polyesters and cellulosics), as a carrier solvent in printing ink, a cleaning agent, an adhesive (in leather, plastics, polyester laminates and polyurethane footwear), in agricultural and veterinary chemicals and in coatings (in paints, varnishes and films).
생산 방법
Methods of manufacturing:The most prevalent 1,4-BD production route worldwide is BASF's Reppe process, which reacts acetylene and formaldehyde. Acetylene reacts with two equivalents of formaldehyde to form 1,4-butynediol, also known as but-2-yne- 1,4-diol. Hydrogenation of 1,4-butynediol gives 1,4-butanediol. 1,4-BD is also made on a large industrial scale by continuous hydrogenation of the 2-butyne- 1,4-diol over modified nickel catalysts. The one-stage flow process is carried out at 80 - 160 deg C and 300 bar.
Mitsubishi uses a three-step process:
(1) the catalytic reaction of butadiene and acetic acid yields 1,4-diacetoxy-2-butene;
(2) subsequent hydrogenation gives 1,4-diacetoxybutane; and
(3) hydrolysis leads to 1,4-butanediol.
일반 설명
Odorless colorless liquid or solid (depending upon temperature).공기와 물의 반응
Highly flammable. 1,4-Butanediol is hygroscopic. Water soluble.반응 프로필
1,4-Butanediol is heat and light sensitive. 1,4-Butanediol reacts with acid chlorides, acid anhydrides and chloroformates; reacts with oxidizing agents and reducing agents. 1,4-Butanediol is incompatible with isocyanates and acids; also incompatible with peroxides, perchloric acid, sulfuric acid, hypochlorous acid, nitric acid, caustics, acetaldehyde, nitrogen peroxide and chlorine.위험도
Toxic by ingestion.건강위험
The acute toxic effects are mild. 1,4-Butanediolis less toxic than its unsaturate analogs,butenediol and the butynediol. The oralLD50 value in white rats and guinea pigsis ~2 mL/kg. The toxic symptoms fromingestion may include excitement, depressionof the central nervous system, nausea, anddrowsiness.화재위험
Nonflammable liquid, flash point (open cup) 121°C.Safety Profile
A human poison by an unspecified route. Moderately toxic byingestion and intraperitoneal routes. Human systemic effects: altered sleep time. Combustible when exposed to heat or flame. To fight fire, use alcohol foam, mist, foam, CO2, dry chemical. Incompatible with oxidizing materials. When heated to decomposition it emits acrid smoke and fumes.Solubility in water
1,4-Butanediol is soluble in water, alcohols, esters, ketones, glycol ethers and glycol ether acetates (Butanediols, Butenediol, and Butynediol).Purification Methods
Distil the glycol and store it over Linde type 4A molecular sieves, or crystallise it twice from anhydrous diethyl ether/acetone, and redistil it. It has been recrystallised from the melt and doubly distilled in vacuo in the presence of Na2SO4. [Beilstein 1 IV 2515.]1,4-부탄디올 준비 용품 및 원자재
원자재
1,3-부타디엔
2,3-부탄디온
포르말린
니켈
클로로프렌
1,4-부틴디올
아세틸렌
cis-1,4-Dichloro-2-butene
3-hydroxy-2-methyl propionaldehyde
다이메틸말리에이트
2-HYDROXYTETRAHYDROFURAN
준비 용품
1,4-부탄디올 공급 업체
글로벌( 768)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 |
kathy@hbyinsheng.com | China | 3582 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 |
info@longyupharma.com | China | 2531 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 |
ada@sh-teruiop.com | China | 893 | 58 |
Dorne Chemical Technology co. LTD | +86-13583358881 +86-18560316533 |
Ethan@dornechem.com | China | 294 | 58 |
Nanjing Deda New Material Technology Ltd. | +8613223281135 |
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Wuhan Ruichi Technology Co., Ltd | +8613545065237 |
admin@whrchem.com | China | 164 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-199-55145978 +8619955145978 |
sales8@anhuiyiao.com | China | 253 | 58 |
Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 |
Sara@xmwonderfulbio.com | China | 305 | 58 |