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뷰티로락톤 구조식 이미지
카스 번호:
BLO;GBL;6480;BLON;GBL-EL;c-1070;gamma-BL;CadionGr;FEMA 3291;Butanolid
포뮬러 무게:
MOL 파일:

뷰티로락톤 속성

−45 °C(lit.)
끓는 점
204-205 °C(lit.)
1.12 g/mL at 25 °C(lit.)
증기 밀도
3 (vs air)
1.5 mm Hg ( 20 °C)
n20/D 1.436(lit.)
209 °F
저장 조건
물리적 상태
JECFA Number
Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents.
CAS 데이터베이스
96-48-0(CAS DataBase Reference)
2(3H)-Furanone, dihydro-(96-48-0)
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,F
위험 카페고리 넘버 22-36-67-41-20/21/22-11
안전지침서 26-36-39-36/37-16
WGK 독일 1
RTECS 번호 LU3500000
자연 발화 온도 851 °F
HS 번호 29322980
유해 물질 데이터 96-48-0(Hazardous Substances Data)
독성 LD50 orally in rats: 17.2 ml/kg (Smyth)
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 P264, P270, P301+P312, P330, P501
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 P264, P280, P302+P352, P321,P332+P313, P362
H318 눈에 심한 손상을 일으킴 심한 눈 손상 또는 자극성 물질 구분 1 위험 P280, P305+P351+P338, P310
H336 졸음 또는 현기증을 일으킬 수 있음 특정표적장기 독성 물질(1회 노출);마취작용 구분 3 경고 P261, P271, P304+P340, P312,P403+P233, P405, P501
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P321 (…) 처치를 하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

뷰티로락톤 MSDS


뷰티로락톤 C화학적 특성, 용도, 생산


GBL는 일반적인 용매 그리고 시약 화학에 있는 뿐 아니라 사용되는 몇몇 젖은 알루미늄 전해질 축전기에 있는 flavouring, 세탁 용제, superglue 제거제, 및 용매로입니다. 인간에서는 그것은 GHB를 위한 프로드러그로 작동하고, 알콜과 유사한 효력을 가진 레크리에이션 취하게 하는 것으로 사용됩니다.


물에 용해되는 GBL은 향료로, 세정 용제로, 초 접착제 제거제로, 일부 습식 알루미늄 전해 커패시터에서 용제로 사용되는 것과 마찬가지로 화학 분야의 일반적인 용제 및 시약입니다.


(1) GBL을 사용하여 α- 피 롤리 돈, 1- 메틸 -2- 피 롤리 디논, 폴리 비닐 피 롤리 돈 및 α- 아세틸 -γ- 부티로 락톤 등을 제조 할 수있다. (2) GBL은 비타민과 롤리 프린의 중간체로서 시프 로플 록 사신 (ciprofloxacin)과 인터페론 (interferon) 생산에 사용되는 마취 및 진정제로 사용할 수 있습니다. (3) GBL은 식물 성장 자극제와 살충제의 중간체이다. (4) GBL은 좋은 산화 방지제, 가소제, 추출제, 흡착제, 분산제, 정착 제 및 경화제입니다. 또한 배터리, 커패시터 및 컬러 필름 개발에도 사용할 수 있습니다.


Dihydro-2(3H)-furanone. An endogenous neuroregulator made from gamma-amino butyrate and the precursor of gamma hydroxybutyrate. It causes selective increase of brain dopamine by inhibiting its release from nerve terminals. The compound has sedative properties at low doses and produces surgical anesthesia at high doses. It is also used as an industrial solvent and precursor.

화학적 성질

γ-Butyrolactone has a faint, sweet, aromatic, slightly buttery odor.

화학적 성질

colourless oily liquid

화학적 성질

Oily, colorless, clear liquid. Faint, pleasant odor.


Reported found as a constituent in coffee aroma; a volatile flavor component in roasted filberts as well. Also reported found in tomato, potato, soybeans, beans, vinegar, mushrooms, roasted chicken, beef, cider, beer, wine, scallops and clams.


r-butyrolactone is one kind of important fine chemicalintermediate, simultaneously also is one kind of performance fine highboiling point solvent, ideal antioxidant, plasticizer,extracting agent, absorbent, dispersing agent, solid stain, Coagulation Reagent.


Intermediate in the synthesis of polyvinylpyrrolidone, DL-methionine, piperidine, phenylbutyric acid, thiobutyric acids. Solvent for polyacrylonitrile, cellulose acetate, methyl methacrylate polymers, polystyrene. Constituent of paint removers, textile aids, drilling oils.


ChEBI: A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.

제조 방법

From acetylene and formaldehyde, also from a number of alternative sources; ethylene chlorohydrin, glutamic acid, γ-hydroxybutyric acid solutions, tetrahydrofuran, vinyl-acetic acid.

Aroma threshold values

Detection: 20 to 50 ppm

Taste threshold values

Taste characteristic at 75 ppm: milky, creamy with fruity peach-like afternotes.

일반 설명

Clear colorless oily liquid with a pleasant odor.

공기와 물의 반응

Hygroscopic. Soluble in water.

반응 프로필

gamma-Butyrolactone can react with oxidizing materials, inorganic acids and bases, alcohols and amines. Rapidly hydrolyzed by bases and slowly hydrolyzed by acids. gamma-Butyrolactone is volatile with steam. . The combination of the lactone, butanol, 2,4-dichlorophenol, and sodium hydroxide in the attempted synthesis of 2,4-dichlorophenoxybutyric acid caused a thermal runaway reaction that eventually exploded, [CISHC Chem. Safety Summ., 1977, 48, 3].


Toxic by ingestion. Questionable carcino- gen.


gamma-Butyrolactone is combustible.

Safety Profile

Moderately toxic by ingestion, intravenous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data by skin contact. Mutation data reported. Less acutely toxic than ppropiolactone. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, alcohol foam, CO2, dry chemical. Potentially explosive reaction with butanol + 2,4 dichlorophenol + sodium hydroxide. When heated to decomposition it emits acrid and irritating fumes.

잠재적 노출

Used as a chemical intermediate for making other chemicals, including pesticides, cosmetics, and pharmaceuticals; as a solvent for paint, nail polish removers, and industrial chemicals. Used in electronics, drilling and petroleum industries as a stabilizer and solvent. Used as a flavoring agent in various foods and beverages, including grains and breakfast foods, candy, and alcoholic and nonalcoholic drinks. Drug of abuse: the United States Food and Drug Administration has warned the public not to purchase or consume products, containing gamma-butyrolactone (GBL). FDA has also asked the companies that manufacture these products to voluntarily recall them. The agency has received reports of serious health problems—some that are potentially life-threatening—associated with the use of these products. Although labeled as dietary supplements and marketed under various brand names, these products are illegally marketed unapproved new drugs. False advertising claims include building muscles, improved physical performance, enhanced sex, reduced stress and induced sleep

운송 방법

Listed by some sources as unregulated. UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1—Poisonous materials, Technical Name Required.

Purification Methods

Dry the lactone over anhydrous CaSO4, then fractionally distil it. Handle it in a fume cupboard due to its TOXICITY. [Beilstein 17 V 7.]

비 호환성

4-Butyrolactone is incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, alcohols, amines, strong and inorganic acids, strong bases. Rapidly hydrolyzed by bases and slowly hydrolyzed by acids. It is hygroscopic and volatile with steam. Combustible; vapor may form explosive mixture with air.

폐기물 처리

Use a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator. All federal, state, and local environmental regulations must be observed.

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