4-Benzylpiperidine
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4-Benzylpiperidine 속성
- 녹는점
- 6-7 °C (lit.)
- 끓는 점
- 279 °C (lit.)
- 밀도
- 0.997 g/mL at 25 °C (lit.)
- 굴절률
- n
20/D 1.537(lit.)
- 인화점
- >230 °F
- 저장 조건
- Store below +30°C.
- 물리적 상태
- 점성 액체
- 산도 계수 (pKa)
- 10.58±0.10(Predicted)
- 색상
- 무색~황색으로 투명함
- BRN
- 132339
- CAS 데이터베이스
- 31252-42-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | TM4728000 | ||
| TSCA | Yes | ||
| 위험 등급 | IRRITANT | ||
| HS 번호 | 29333990 |
4-Benzylpiperidine C화학적 특성, 용도, 생산
화학적 성질
clear colourless to yellow viscous liquid.용도
4-Benzylpiperidine was studied as acid corrosion inhibitor for iron. It was also used to study potential utility of dopamine-welective releaser as a treatment for cocaine dependence. In an assay of cocaine discrimination, 4-Benzylpiperidine had the most rapid onset and shortest duration of action.제조 방법
4-Benzylpiperidine can be prepared by reacting 4-cyanopyridine with toluene. Catalytic hydrogenation of the pyridine ring then completes the synthesis.주요 응용
Reactant for synthesis of:Antiproliferatives
GABA uptake inhibitors
Pyridines
Histamine H3 antagonists
Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases
Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution
일반 설명
4-Benzylpiperidine is dopamine-selective releaser. It is a potential candidate for treatments for cocaine dependence.Biochem/physiol Actions
4-Benzylpiperidine inhibits the activity of rat brain monoamine oxidase-A and -B, with IC50 values of 0.02 mM and 2 mM respectively. It acts as a monoamine releasing agent with 20- to 48-fold selectivity for releasing dopamine versus serotonin. It is most efficacious as a releaser of norepinephrine, with an ec50 of 109/41.4/5246nM for DA/NE/5HT, respectively . It has a fast onset of action and a short duration. It also functions as a monoamine oxidase inhibitor (MAOI) with preference for MAO-A.4-Benzylpiperidine 준비 용품 및 원자재
원자재
다이에틸렌 글리콜
무수초산
수산화칼륨
염화칼슘
탄산 칼륨
하이드라진, 모노수화물
트리플루오로아세트 산
나트륨 붕소수화물
염화알루미늄
테트라하이드로푸란
벤젠
1,2-디클로로에탄
수소화 리튬알미늄
염산
이소니페코틱산
디클로로메탄
수산화나트륨
트라이에틸실레인
이소프로필에테르
이소프로필알코올
염화 티오닐
준비 용품
4-Benzylpiperidine 공급 업체
글로벌( 198)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 |
mcbio_sales@163.com | China | 2255 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 |
info@edengenechem.com | China | 2169 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 |
1015@dideu.com | China | 2263 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 |
joe@yuhengpharm.com | CHINA | 21149 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34572 | 58 |
4-Benzylpiperidine 관련 검색:
1-벤질-4-피페리돈 4-아미노-1-벤질피페리딘
4-(4-FLUOROBENZOYL)PIPERIDINE P-TOLUENESULFONATE
KETANSERIN TARTRATE
4-(4-Fluorobenzoyl)piperidine hydrochloride
PIRENPERONE
(4-METHOXYPHENYL)(4-PIPERIDYL)METHANONE HYDROCHLORIDE
4-BENZYL-4-HYDROXYPIPERIDINE
alpha,alpha-Diphenyl-4-piperidinomethanol
Ifenprodil
Terfenadine
4-BENZOYLPIPERIDINE HYDROCHLORIDE
BENZETIMIDE
Diphenylpiperidin-4-ylmethanol hydrochloride
Ketanserin
4-Benzylpiperidine
1-(2-Aminoethyl)-4-benzylpiperidine
METHYL 1-BENZYL-PIPERIDINE-3-CARBOXYLATE