Aspartate
- CAS No.
- 56-84-8
- Chemical Name:
- Aspartate
- Synonyms
- ASPARTIC ACID;ASP;ASPARTATE;L-ASP;H-ASP-OH;Aspartic;Asparaginic acid;(S)-2-AMINOSUCCINIC ACID;L-Asp-OH;L-ASPARGINE
- CBNumber:
- CB00127482
- Molecular Formula:
- C4H7NO4
Lewis structure
- Molecular Weight:
- 133.1
- MDL Number:
- MFCD00002616
- MOL File:
- 56-84-8.mol
- MSDS File:
- SDS
| Melting point | >300 °C (dec.)(lit.) |
|---|---|
| alpha | 25 º (c=8, 6N HCl) |
| Boiling point | 245.59°C (rough estimate) |
| Density | 1.66 |
| refractive index | 1.4540 (estimate) |
| FEMA | 3656 | L-ASPARTIC ACID |
| storage temp. | Store below +30°C. |
| solubility | H2O: 5 mg/mL |
| form | powder |
| pka | 1.99(at 25℃) |
| color | White |
| PH | 2.5-3.5 (4g/l, H2O, 20℃) |
| Odor | acid taste |
| Odor Type | odorless |
| optical activity | [α]20/D +24.7±1°, c = 5% in 5 M HCl |
| Water Solubility | 5 g/L (25 ºC) |
| λmax |
λ: 260 nm Amax: 0.20 λ: 280 nm Amax: 0.10 |
| JECFA Number | 1429 |
| Merck | 14,840 |
| BRN | 1723530 |
| Stability | Stable. Combustible. Incompatible with strong oxidising agents. |
| InChIKey | CKLJMWTZIZZHCS-REOHCLBHSA-N |
| LogP | -0.67 |
| Substances Added to Food (formerly EAFUS) | L-ASPARTIC ACID |
| FDA 21 CFR | 172.320 |
| CAS DataBase Reference | 56-84-8(CAS DataBase Reference) |
| FDA UNII | 30KYC7MIAI |
| NIST Chemistry Reference | Aspartic acid(56-84-8) |
| EPA Substance Registry System | Aspartic acid (56-84-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-24/25-22-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | CI9098500 | |||||||||
| F | 10 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29224995 | |||||||||
| Toxicity | LD50 intraperitoneal in mouse: 6gm/kg | |||||||||
| NFPA 704 |
|
Aspartate price More Price(89)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL80666 | L-Aspartic acid phyproof? Reference Substance | 56-84-8 | 100MG | $262 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.16003 | (S)-(+)-Aspartic acid forsynthesis | 56-84-8 | 100g | $54.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.16003 | (S)-(+)-Aspartic acid forsynthesis | 56-84-8 | 500g | $188 | 2024-03-01 | Buy |
| Sigma-Aldrich | 11189 | L-Aspartic acid BioUltra, ≥99.5% (T) | 56-84-8 | 1kg | $545 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1043819 | Aspartic acid United States Pharmacopeia (USP) Reference Standard | 56-84-8 | 100mg | $447 | 2024-03-01 | Buy |
Aspartate Chemical Properties,Uses,Production
Description
Aspartate is a non-essential amino acid, meaning that it is readily and naturally synthesized by mammals. It is one of the 20 building-block amino acids of proteins, 3-letter code is ASP, one letter code is D. The DNA codons encoding aspartic acid are GAC and GAU.
Chemical Properties
In proteins aspartate sidechains are often hydrogen bonded to form asx turns or asx motifs, which frequently occur at the N-termini of alpha helices.Aspartate, like glutamic acid, is classified as an acidic amino acid, with a pKa of 3.9; however, in a peptide this is highly dependent on the local environment, and could be as high as 14.
Uses
Aspartate is used as an electrolyte supplement for aminophenol transfusion, inorganic ion supplement (K+, Ca+, etc.) and fatigue restorer. Potassium magnesium aspartate injection or oral solution can be used for arrhythmia, premature beat, tachycardia, hypokalemia, hypomagnesemia, heart failure, myocardial infarction, angina pectoris, hepatitis, cirrhosis and other diseases caused by cardiac glycoside poisoning.
Hazard
Low toxicity
Synthesis
Industrially, aspartate is produced by amination of fumarate catalyzed by L-aspartate ammonia-lyase.Racemic aspartic acid can be synthesized from diethyl sodium phthalimidomalonate, (C6H4(CO)2NC(CO2Et)2).
Forms and nomenclature
There are two forms or enantiomers of aspartic acid. Of these two forms, only one, "L-aspartic acid", is directly incorporated into proteins. The biological roles of its counterpart, "D-aspartic acid" are more limited. Where enzymatic synthesis will produce one or the other, most chemical syntheses will produce both forms, "DL-aspartic acid", known as a racemic mixture.
Aspartate Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NINGBO CREATE-BIO ENGINEERING CO.,LTD | +8613906695486 | 13906695486@126.com | China | 1 | 58 |
| Shandong Juchuang Chemical Co., LTD | +undefined15030412209 | admin@juchuangchem.com | China | 387 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 958 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 2991 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 841 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15932 | 58 |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 | bj1@bj-chem.com | China | 298 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9347 | 55 |
View Lastest Price from Aspartate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-05-19 | Lomefoxacin aspartate | US $0.01-1.00 / KG | 1KG | 99% | 50 tons | Shaanxi Dideu Medichem Co. Ltd | |
|
|
2020-05-19 | Lomefloxacin Aspartate
211690-33-4
|
US $0.01-1.00 / KG | 1KG | 99% | 50 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-13 | Aspartate aminotransferase
9000-97-9
|
US $1.00 / KG | 1KG | 98%HPLC | 10 tons | Career Henan Chemical Co |
-
- Lomefoxacin aspartate
- US $0.01-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Lomefloxacin Aspartate
211690-33-4
- US $0.01-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Aspartate aminotransferase
9000-97-9
- US $1.00 / KG
- 98%HPLC
- Career Henan Chemical Co