1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논

1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논
1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논 구조식 이미지
카스 번호:
43121-43-3
한글명:
1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논
동의어(한글):
1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2-부타논;트라이아디메폰
상품명:
Triadimefon
동의어(영문):
Tridimefon;Triadimefone;TRIADIMEPHON;TriadiMefon Standard;ROFON;NUREX;OTRIA;DAYTON;ACIZOL;Amiral
CBNumber:
CB7426290
분자식:
C14H16ClN3O2
포뮬러 무게:
293.75
MOL 파일:
43121-43-3.mol
MSDS 파일:
SDS

1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논 속성

녹는점
82°C
끓는 점
441.9±55.0 °C(Predicted)
밀도
1.2200
증기압
2 x l0-5 Pa (20 °C)
굴절률
1.5388 (estimate)
인화점
11 °C
저장 조건
APPROX 4°C
용해도
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
산도 계수 (pKa)
1.41±0.11(Predicted)
수용성
0.026g/100mL
Merck
13,9666
BRN
619231
NIST
2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1h-1,2,4-triazol-1-yl)-(43121-43-3)
EPA
Triadimefon (43121-43-3)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,N,T,F
위험 카페고리 넘버 22-43-51/53-39/23/24/25-23/24/25-11
안전지침서 24-37-61-45-36/37
유엔번호(UN No.) 2588
WGK 독일 2
RTECS 번호 EL7100000
위험 등급 6.1(b)
포장분류 III
HS 번호 29339900
유해 물질 데이터 43121-43-3(Hazardous Substances Data)
독성 LD50 in male, female rats (mg/kg): 568, 363 orally (Michel, Pourcharesse)
기존화학 물질 KE-05810
그림문자(GHS): GHS hazard pictogramsGHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 알레르기성 피부 반응을 일으킬 수 있음 피부 과민성 물질 구분 1 경고 GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H330 흡입하면 치명적임 급성 독성 물질 흡입 구분 1, 2 위험 GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H410 장기적 영향에 의해 수생생물에 매우 유독함 수생 환경유해성 물질 - 만성 구분 1 경고 GHS hazard pictograms P273, P391, P501
예방조치문구:
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P273 환경으로 배출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P312 삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P302+P352 피부에 묻으면 다량의 물로 씻으시오.
NFPA 704
0
2 0

1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논 MSDS


1-(tert-Butylcarbonyl-(4-chlorophenoxy)methyl)-1H-1,2,4-triazole

1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논 C화학적 특성, 용도, 생산

개요

Triadimefon has been a widely used fungicide on crops and nonfood products since the early 1970s. The metabolite triadimenol is also active and is registered separately for use as seed treatment. Triadimenol has a broad regulatory toxicology database, but its toxicity is considered to be encompassed in that of triadimefon and therefore the same study was used by the United States Environmental Protection Agency (US EPA) in establishing regulatory levels for both pesticides. In nontarget species, dopaminergic neurotoxicity is the primary effect, but with chronic exposures its toxicities include hepatic, carcinogenic, developmental, and reproductive effects.

용도

Triadimefon is an triazole fungicide is used for the management of mango powdery mildew in South Gujarat.

일반 설명

Colorless to pale yellow crystalline solid with a slight odor.

공기와 물의 반응

Insoluble in water.

반응 프로필

Triadimefon is incompatible with strong oxidizing agents and acids. Reacts with acid halides and anhydrides. Also reacts with most active hydrogen compounds .

화재위험

Flash point data for Triadimefon are not available; however, Triadimefon is probably combustible.

농업용

Fungicide: Triadimefon is a systemic fungicide that is used to control powdery mildews, rusts, and other fungi on coffee, seed grasses, cereals, fruits, grapes, vegetables, vines, pineapple, sugar cane, sugar beets, turf, shrubs, and trees. Not approved for use in EU countries. Registered for use in the U.S. U.S. Maximum Allowable Residue Levels for Triadimefon

상품명

ACCOST®; ACIZOL®; AMIRAL®; BAY® 6681-F; BAYLETON®; BAY®-MEB-6447; BAYER® 6681-F; BAYER® MEB-6447; MEB 6447®; PRO-TEK®; ROFON®

Pharmacology

Triadimefon (36) and its alcohol analog triadimenol (37) have been intensively investigated to determine the influence of their enantiomeric difference on fungicidal activity. Between stereoisomeric triadimefon, no significant difference is observed in their fungicidal activity. However, triadimenol, which shows a much higher fungicidal activity than triadimefon, exhibits a clear stereochemistry-dependent activity difference. Greater fungicidal activity is possessed by the (1S, 2R)-isomer (28).

Safety Profile

Poison by ingestion. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx. See also KETONES.

환경귀착

Soil. In a culture study, the microorganism Aspergillus niger degraded 32% of tri- adimefon to triadimenol after 5 days (Clark et al., 1978).
Plant. In soils and plants, triadimefon degrades to triadimenol (Clark et al., 1978; Rouchaud et al., 1981). In barley plants, triadimefon was metabolized to triadimenol and p-chlorophenol (Rouchaud et al., 1981; Rouchaud, 1982). In the grains an
Photolytic. When triadimefon was subjected to UV light for one week, p-chlorophenol, 4-chlorophenyl methyl carbamate and a 1,2,4-triazole formed as products (Clark et al., 1978).

신진 대사 경로

Enzymic reduction of triadimefon is an important pathway in plants, soils and fungi and may be regarded as an activation process, which produces fungicidally active triadimenol. Two diastereoisomers of triadimenol, A and B [( 1RS,2SR)-l-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl) butan-2-ol is referred to as diastereoisomer A; 1RS,2RS- is referred to as diastereoisomer β], are produced in different amounts by plants and fungi and the proportions may differ within the plant. Similar metabolic pathways are followed in mammals where reduction of the keto group yields triadimenol as the principal metabolite and oxidation of the butyl group gives alcohol and carboxylic acid derivatives.

1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논 준비 용품 및 원자재

원자재

준비 용품


1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논 공급 업체

글로벌( 303)공급 업체
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1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논 관련 검색:

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