PI3K 抑制剂

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资讯信息

  • [BKM120 (NVP-BKM120, Buparlisib)]  Buparlisib (BKM120) 2020/10/23
  • [GSK2126458]  Omipalisib (GSK2126458，GSK458) 2020/10/23
  • [BAY 80-6946 (Copanlisib)]  Copanlisib (BAY80–6946) 2020/10/22
  • [GSK2636771]  GSK2636771 2020/10/22
  • [NVP-BGT226]  NVP-BGT226 2020/10/22
  • [(S)-1-[4-[[2-(2-氨基嘧啶-5-基)-7-甲基-4-(吗啉-4-基)噻吩并[3,2-D]嘧啶-6-基]甲基]哌嗪-1-基]-2-羟基丙-1-酮]  Apitolisib (GDC-0980) 2020/10/22
  • [2-(2-二氟甲基苯并咪唑-1-基)-4,6-二吗啉基-1,3,5-三嗪]  ZSTK474 2020/10/21
  • [2-甲基-2-[4-[3-甲基-2-氧代-8-(喹啉-3-基)-2,3-二氢咪唑并[4,5-C]喹啉-1-基]苯基]丙腈]  Dactolisib 2020/10/21

    • PI3K 抑制剂

    BEZ235 (NVP-BEZ235, Dactolisib)LY294002/PI3K抑制剂Pictilisib (GDC-0941)CAL-101BKM120 (NVP-BKM120, Buparlisib)GSK2126458; GSK-2126458PI-103Apitolisib (GDC-0980, RG7422)5-(6-喹喔啉亚甲基)-2,4-噻唑啉二酮2-(2-二氟甲基苯并咪唑-1-基)-4,6-二吗啉基-1,3,5-三嗪IC-87114XL147PIK-90Gedatolisib (PF-05212384, PKI-587)PIK-93YM201636IPI-145GSK26367715-[[5-(4-氟-2-羟基苯基)-2-呋喃基]亚甲基]-2,4-噻唑烷二酮AZD64825-[(2,2-二氟-1,3-苯并二恶茂-5-基)亚甲基]噻唑烷-2,4-二酮GSK1059615TG100-1155-(2-氨基-8-氟[1,2,4]三唑并[1,5-A]吡啶-6-基)-N-(叔丁基)-3-吡啶磺酰胺XL765PIK-75PKI-402A66VS-5584BGT226 (NVP-BGT226)BAY 80-6946 (Copanlisib)PIK-294[5-[7-甲磺酰基-2-(吗啉-4-基)-6,7-二氢-5H-吡咯并[2,3-D]嘧啶-4-基]嘧啶-2-基]胺PI-3065PIK-293TG 100713,3-(2,4-DIAMINO-6-PTERIDINYL)-PHENOLCAY10505HS-173GNE-317